Quarterly report pursuant to Section 13 or 15(d)

Share-based compensation - Share-based Compensation Expense (Details)

v3.19.2
Share-based compensation - Share-based Compensation Expense (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Total share-based compensation expense included in the consolidated statements of operations        
Total share-based compensation expense $ 3,196 $ 4,079 $ 6,675 $ 8,411
Research and development        
Total share-based compensation expense included in the consolidated statements of operations        
Total share-based compensation expense 786 2,071 2,807 4,285
General and administrative        
Total share-based compensation expense included in the consolidated statements of operations        
Total share-based compensation expense $ 2,410 $ 2,008 $ 3,868 $ 4,126