Quarterly report [Sections 13 or 15(d)]

Segment reporting - Segment profit or loss (Details)

v3.25.1
Segment reporting - Segment profit or loss (Details) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Segment reporting    
Revenue $ 7,285 $ 5,678
Cost of goods sold (879)  
Total operating expenses (53,018) (54,939)
Loss from operations (45,733) (49,261)
Interest income 910 1,345
Interest expense (1,881)  
Other income (expense), net (305) (61)
Income tax expense (575) (526)
Net loss attributable to ordinary shareholders (47,584) (48,503)
Research    
Segment reporting    
Total operating expenses (2,108) (3,800)
CMC and Quality    
Segment reporting    
Total operating expenses (12,085) (14,200)
Biomarkers    
Segment reporting    
Total operating expenses (1,222) (2,500)
Development and Compliance    
Segment reporting    
Total operating expenses (10,550) (12,600)
Infrastructure management and facilities    
Segment reporting    
Total operating expenses (7,339) (7,700)
Commercial and Commercial planning    
Segment reporting    
Total operating expenses (4,398) (2,600)
Support and corporate functions    
Segment reporting    
Total operating expenses (12,639) (9,000)
Other segment expenses    
Segment reporting    
Total operating expenses $ (1,798) $ (2,539)