Quarterly report pursuant to Section 13 or 15(d)

Accrued expenses and other current liabilities (Details)

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Accrued expenses and other current liabilities (Details) - USD ($)
$ in Thousands
Sep. 30, 2018
Dec. 31, 2017
Accrued expenses and other current liabilities    
Accrued clinical and development expenditure $ 9,566 $ 10,065
Accrued employee expenses 6,897 6,592
VAT 3,388 5,741
Other accrued expenditure 3,812 4,446
Other liabilities 651 357
Total $ 24,314 $ 27,201