Annual report pursuant to Section 13 and 15(d)

Revenue - Revenue from contracts with customers (Details)

v3.24.0.1
Revenue - Revenue from contracts with customers (Details)
1 Months Ended 3 Months Ended 12 Months Ended
Dec. 31, 2022
USD ($)
$ / £
Nov. 30, 2022
USD ($)
Dec. 31, 2023
USD ($)
$ / £
Sep. 30, 2023
USD ($)
Dec. 31, 2023
USD ($)
$ / £
Dec. 31, 2022
USD ($)
$ / £
Dec. 31, 2021
USD ($)
$ / £
Jun. 30, 2023
USD ($)
Jan. 01, 2022
USD ($)
Revenue                  
Revenue         $ 60,281,000 $ 27,148,000 $ 6,149,000    
Deferred revenue decrease           6,379,000 15,010,000    
Deferred revenue $ 184,412,000   $ 178,033,000   178,033,000 $ 184,412,000 199,422,000   $ 184,412,000
Amount of increase in deferred income caused by the change in the exchange rate         $ 7,174,000   $ (20,601,000)    
Exchange rate | $ / £ 1.21   1.27   1.27 1.21 1.35    
Revenue recognized in the period         $ 59,072,000 $ 17,648,000      
Development revenue                  
Revenue                  
Revenue         60,281,000 $ 27,148,000 $ 6,149,000    
GSK Collaboration And License Agreement                  
Revenue                  
Upfront payment by GSK for Termination and Transfer Agreement               $ 9,613,000  
Milestone payments received     $ 15,226,000 $ 3,727,000          
Genentech, Inc.                  
Revenue                  
Milestone payments received $ 20,000,000 $ 15,000,000              
Aggregate amount of the transaction price that is allocated to performance obligations that are unsatisfied or partially satisfied under the agreements     $ 312,747,000   $ 312,747,000