Quarterly report pursuant to Section 13 or 15(d)

Contingencies and commitments - Collaborations and License Agreements (Details)

v3.7.0.1
Contingencies and commitments - Collaborations and License Agreements (Details) - USD ($)
 1 Months Ended 3 Months Ended 12 Months Ended
Jun. 16, 2016
Feb. 29, 2016
Nov. 30, 2015
Mar. 31, 2017
Dec. 31, 2012
Sep. 26, 2016
Collaboration and License Agreement            
Milestone payments       $ 0    
ThermoFisher            
Collaboration and License Agreement            
Supply contract agreement period (in years) 5 years          
MD Anderson Strategic Alliance            
Collaboration and License Agreement            
Upfront license fees       3,412,000    
Clinical trials commitment | MD Anderson Strategic Alliance | Minimum            
Collaboration and License Agreement            
Potential milestone payments           $ 19,644,000
Collaborative arrangement | Universal Cells, Inc.            
Collaboration and License Agreement            
Upfront license and startup fees     $ 2,500,000      
Milestone payments   $ 3,000,000   500,000    
Potential milestone payments       $ 43,500,000    
Collaborative arrangement | Life Technologies Corp            
Collaboration and License Agreement            
Upfront license fees         $ 1,000,000  
Minimum annual royalties as a percentage of prior year running royalties (as a percent)       50.00%