Quarterly report pursuant to Section 13 or 15(d)

Accrued expenses and other current liabilities (Details)

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Accrued expenses and other current liabilities (Details) - USD ($)
$ in Thousands
Jun. 30, 2018
Dec. 31, 2017
Accrued expenses and other current liabilities    
Accrued clinical and development expenditure $ 11,357 $ 10,065
Accrued employee expenses 5,419 6,592
VAT   5,741
Other accrued expenditure 4,238 4,446
Other liabilities 443 357
Total $ 21,457 $ 27,201