Quarterly report pursuant to Section 13 or 15(d)

Share-based compensation - Share-based Compensation Expense (Details)

v3.10.0.1
Share-based compensation - Share-based Compensation Expense (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Total share-based compensation expense included in the consolidated statements of operations        
Total share-based compensation expense $ 4,042 $ 2,072 $ 12,453 $ 4,757
Research and development        
Total share-based compensation expense included in the consolidated statements of operations        
Total share-based compensation expense 2,053 871 6,338 2,229
General and administrative        
Total share-based compensation expense included in the consolidated statements of operations        
Total share-based compensation expense $ 1,989 $ 1,201 $ 6,115 $ 2,528