Quarterly report pursuant to Section 13 or 15(d)

Share-based compensation - Share-based Compensation Expense (Details)

v3.19.1
Share-based compensation - Share-based Compensation Expense (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Total share-based compensation expense included in the consolidated statements of operations    
Total share-based compensation expense $ 3,479 $ 4,672
Research and development    
Total share-based compensation expense included in the consolidated statements of operations    
Total share-based compensation expense 2,021 2,554
General and administrative    
Total share-based compensation expense included in the consolidated statements of operations    
Total share-based compensation expense $ 1,458 $ 2,118