Share-based compensation - Share-based Compensation Expense (Details) - USD ($) $ in Thousands |
3 Months Ended | |
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Mar. 31, 2019 |
Mar. 31, 2018 |
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| Total share-based compensation expense included in the consolidated statements of operations | ||
| Total share-based compensation expense | $ 3,479 | $ 4,672 |
| Research and development | ||
| Total share-based compensation expense included in the consolidated statements of operations | ||
| Total share-based compensation expense | 2,021 | 2,554 |
| General and administrative | ||
| Total share-based compensation expense included in the consolidated statements of operations | ||
| Total share-based compensation expense | $ 1,458 | $ 2,118 |
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- Definition Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- References No definition available.
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