Quarterly report pursuant to Section 13 or 15(d)

UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

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UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Cash flows from operating activities    
Net loss $ (119,232) $ (93,479)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 4,333 5,151
Share-based compensation expense 15,802 7,352
Unrealized foreign exchange gains (213) (1,102)
Amortization on available-for-sale debt securities 4,094 2,798
Other 2,239 737
Changes in operating assets and liabilities:    
Increase/(decrease) in receivables and other operating assets (31,809) 3,345
Decrease in non-current operating assets   2,291
Decrease in payables and other current liabilities (109) (117)
Increase in deferred revenue 1,696 48,649
Net cash used in operating activities (123,199) (24,375)
Cash flows from investing activities    
Acquisition of property, plant and equipment (4,558) (1,174)
Acquisition of intangibles (181) (496)
Maturity or redemption of marketable securities 190,393 78,915
Investment in marketable securities (81,363) (363,777)
Net cash provided by (used in) investing activities 104,291 (286,532)
Cash flows from financing activities    
Proceeds from issuance of common stock from offerings, net of commissions and issuance costs 2,529 334,388
Proceeds from exercise of stock options 707 5,541
Net cash provided by financing activities 3,236 339,929
Effect of currency exchange rate changes on cash, cash equivalents and restricted cash (1,177) (1,023)
Net (decrease) increase in cash, cash equivalents and restricted cash (16,849) 27,999
Cash, cash equivalents and restricted cash at start of period 61,484 54,908
Cash, cash equivalents and restricted cash at end of period $ 44,635 $ 82,907