Annual report pursuant to Section 13 and 15(d)

Contingencies and commitments - Alpine Collaboration Agreement (Details)

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Contingencies and commitments - Alpine Collaboration Agreement (Details) - Research and development - Alpine Immune Sciences Inc. - USD ($)
1 Months Ended 12 Months Ended
Jun. 30, 2019
Dec. 31, 2022
Dec. 31, 2020
Contingencies and commitments      
Upfront license fees $ 2,000,000   $ 2,000,000
Milestone payments   $ 1,000,000  
Maximum      
Contingencies and commitments      
Potential milestone payments $ 288,000,000