Quarterly report pursuant to Section 13 or 15(d)

UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF CHANGE IN EQUITY

v3.22.2.2
UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF CHANGE IN EQUITY - USD ($)
$ in Thousands
Common stock
Additional paid in capital
Accumulated other comprehensive (loss) income
Accumulated deficit
Total
Balance at the beginning of the period, shares at Dec. 31, 2020 928,754,958        
Balance at the beginning of the period at Dec. 31, 2020 $ 1,325 $ 935,706 $ (10,048) $ (585,756) $ 341,227
Increase (Decrease) in Stockholders' Equity          
Net loss       (37,763) (37,763)
Other comprehensive gain (loss)     (176)   (176)
Issuance of shares upon exercise of stock options $ 6 529     535
Issuance of shares upon exercise of stock options (in shares) 4,062,210        
Share-based compensation expense   5,334     5,334
Balance at the end of the period at Mar. 31, 2021 $ 1,331 941,569 (10,224) (623,519) 309,157
Balance at the end of the period, shares at Mar. 31, 2021 932,817,168        
Balance at the beginning of the period, shares at Dec. 31, 2020 928,754,958        
Balance at the beginning of the period at Dec. 31, 2020 $ 1,325 935,706 (10,048) (585,756) 341,227
Increase (Decrease) in Stockholders' Equity          
Net loss         (119,232)
Balance at the end of the period at Sep. 30, 2021 $ 1,337 954,732 (10,098) (704,988) 240,983
Balance at the end of the period, shares at Sep. 30, 2021 937,049,820        
Balance at the beginning of the period, shares at Mar. 31, 2021 932,817,168        
Balance at the beginning of the period at Mar. 31, 2021 $ 1,331 941,569 (10,224) (623,519) 309,157
Increase (Decrease) in Stockholders' Equity          
Net loss       (39,068) (39,068)
Other comprehensive gain (loss)     (161)   (161)
Issuance of shares upon exercise of stock options $ 1 42     43
Issuance of shares upon exercise of stock options (in shares) 350,628        
Issue of shares under At The Market sales agreement, net of commission and expenses $ 4 2,515     2,519
Issue of shares under At The Market sales agreement, net of commission and expenses (in shares) 3,069,330        
Share-based compensation expense   5,449     5,449
Balance at the end of the period at Jun. 30, 2021 $ 1,336 949,575 (10,385) (662,587) 277,939
Balance at the end of the period, shares at Jun. 30, 2021 936,237,126        
Increase (Decrease) in Stockholders' Equity          
Net loss       (42,401) (42,401)
Other comprehensive gain (loss)     287   287
Issuance of shares upon exercise of stock options $ 1 128     129
Issuance of shares upon exercise of stock options (in shares) 812,694        
Issue of shares under At The Market sales agreement, net of commission and expenses   10     10
Share-based compensation expense   5,019     5,019
Balance at the end of the period at Sep. 30, 2021 $ 1,337 954,732 (10,098) (704,988) $ 240,983
Balance at the end of the period, shares at Sep. 30, 2021 937,049,820        
Balance at the beginning of the period, shares at Dec. 31, 2021 937,547,934       937,547,934
Balance at the beginning of the period at Dec. 31, 2021 $ 1,337 959,611 (11,142) (743,846) $ 205,960
Increase (Decrease) in Stockholders' Equity          
Net loss       (50,265) (50,265)
Other comprehensive gain (loss)     1,829   1,829
Issuance of shares upon exercise of stock options $ 5 30     35
Issuance of shares upon exercise of stock options (in shares) 3,318,072        
Share-based compensation expense   5,586     5,586
Balance at the end of the period at Mar. 31, 2022 $ 1,342 965,227 (9,313) (794,111) $ 163,145
Balance at the end of the period, shares at Mar. 31, 2022 940,866,006        
Balance at the beginning of the period, shares at Dec. 31, 2021 937,547,934       937,547,934
Balance at the beginning of the period at Dec. 31, 2021 $ 1,337 959,611 (11,142) (743,846) $ 205,960
Increase (Decrease) in Stockholders' Equity          
Net loss         (136,206)
Balance at the end of the period at Sep. 30, 2022 $ 1,394 985,312 6,683 (880,052) $ 113,337
Balance at the end of the period, shares at Sep. 30, 2022 982,719,936       982,719,936
Balance at the beginning of the period, shares at Mar. 31, 2022 940,866,006        
Balance at the beginning of the period at Mar. 31, 2022 $ 1,342 965,227 (9,313) (794,111) $ 163,145
Increase (Decrease) in Stockholders' Equity          
Net loss       (44,520) (44,520)
Other comprehensive gain (loss)     8,270   8,270
Issuance of shares upon exercise of stock options $ 1       1
Issuance of shares upon exercise of stock options (in shares) 759,336        
Issue of shares under At The Market sales agreement, net of commission and expenses $ 44 9,932     9,976
Issue of shares under At The Market sales agreement, net of commission and expenses (in shares) 35,134,182        
Share-based compensation expense   5,045     5,045
Balance at the end of the period at Jun. 30, 2022 $ 1,387 980,204 (1,043) (838,631) 141,917
Balance at the end of the period, shares at Jun. 30, 2022 976,759,524        
Increase (Decrease) in Stockholders' Equity          
Net loss       (41,421) (41,421)
Other comprehensive gain (loss)     7,726   7,726
Issuance of shares upon exercise of stock options $ 1 5     6
Issuance of shares upon exercise of stock options (in shares) 1,005,558        
Issue of shares under At The Market sales agreement, net of commission and expenses $ 6 1,440     1,446
Issue of shares under At The Market sales agreement, net of commission and expenses (in shares) 4,954,854        
Share-based compensation expense   3,663     3,663
Balance at the end of the period at Sep. 30, 2022 $ 1,394 $ 985,312 $ 6,683 $ (880,052) $ 113,337
Balance at the end of the period, shares at Sep. 30, 2022 982,719,936       982,719,936