Quarterly report pursuant to Section 13 or 15(d)

Contingencies and commitments - Collaborations and License Agreements (Details)

v3.8.0.1
Contingencies and commitments - Collaborations and License Agreements (Details) - USD ($)
$ in Thousands
 1 Months Ended 9 Months Ended 12 Months Ended
Jun. 16, 2016
Feb. 29, 2016
Nov. 30, 2015
Sep. 30, 2017
Dec. 31, 2012
Mar. 31, 2017
Sep. 26, 2016
ThermoFisher              
Collaboration and License Agreement              
Supply contract agreement period (in years) 5 years            
MD Anderson Strategic Alliance              
Collaboration and License Agreement              
Upfront license fees       $ 3,412      
Clinical trials commitment | MD Anderson Strategic Alliance | Minimum              
Collaboration and License Agreement              
Potential milestone payments             $ 19,644
Collaborative arrangement | Universal Cells, Inc.              
Collaboration and License Agreement              
Potential milestone payments           $ 43,500  
Upfront license and startup fees     $ 2,500        
Milestone payments   $ 3,000   $ 800      
Collaborative arrangement | Life Technologies Corp              
Collaboration and License Agreement              
Upfront license fees         $ 1,000    
Minimum annual royalties as a percentage of prior year running royalties (as a percent)       50.00%