Quarterly report pursuant to Section 13 or 15(d)

Share-based compensation - Share-based Compensation Expense (Details)

v3.8.0.1
Share-based compensation - Share-based Compensation Expense (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Total share-based compensation expense included in the consolidated statements of operations        
Total share-based compensation expense $ 3,199 $ 2,286 $ 7,956 $ 6,825
Research and development        
Total share-based compensation expense included in the consolidated statements of operations        
Total share-based compensation expense 1,683 1,170 3,912 3,438
General and administrative        
Total share-based compensation expense included in the consolidated statements of operations        
Total share-based compensation expense $ 1,516 $ 1,116 $ 4,044 $ 3,387