Annual report pursuant to Section 13 and 15(d)

Income taxes (Tables)

v3.22.0.1
Income taxes (Tables)
12 Months Ended
Dec. 31, 2021
Income taxes  
Schedule of loss before income tax expenses

Loss before income tax expense is as follows (in thousands):

​

​

​

​

​

​

​

​

​

​

​

​

Year ended

​

Year ended

​

Year ended

​

​

December 31, 

​

December 31, 

​

December 31, 

​

    

2021

    

2020

    

2019

U.S.

​

$

1,625

​

$

(1,359)

​

$

(494)

U.K.

​

​

(158,924)

​

​

(128,571)

​

​

(136,429)

Loss before income tax expense

​

$

(157,299)

​

$

(129,930)

​

$

(136,923)

Schedule of components of income tax expense

The components of income tax expense are as follows (in thousands):

​

​

​

​

​

​

​

​

​

​

​

​

Year ended

​

Year ended

​

Year ended

​

​

December 31, 

​

December 31, 

​

December 31, 

​

    

2021

    

2020

    

2019

United States:

​

​

​

​

​

​

​

​

​

Federal

​

$

791

​

$

162

​

$

242

State and local

​

​

—

​

​

—

​

​

—

U.K.

​

​

—

​

​

—

​

​

—

Total current tax expense

​

​

791

​

​

162

​

​

242

​

​

​

​

​

​

​

​

​

​

United States:

​

​

​

​

​

​

​

​

​

Federal

​

​

—

​

​

—

​

​

—

State and local

​

​

—

​

​

—

​

​

—

U.K.

​

​

—

​

​

—

​

​

—

Total deferred tax expense

​

​

—

​

​

—

​

​

—

Total income tax expense

​

$

791

​

$

162

​

$

242

​

Schedule of deferred tax assets and liabilities

As of December 31, 2021 and 2020 the tax effects of temporary differences and carryforwards that give rise to deferred tax assets and liabilities were as follows (in thousands):

​

​

​

​

​

​

​

​

​

December 31, 

​

December 31, 

​

    

2021

    

2020

Deferred tax liabilities

​

​

​

​

​

​

Property, plant and equipment:

​

$

(922)

​

$

(796)

Operating lease right-of-use assets

​

​

(1,757)

​

​

(2,009)

Other

​

​

(238)

​

​

(156)

Total

​

​

(2,917)

​

​

(2,961)

​

​

​

​

​

​

​

Deferred tax assets

​

​

​

​

​

​

Share-based compensation expense

​

​

15,584

​

​

9,292

Intangibles

​

​

2,401

​

​

1,745

Operating lease liabilities

​

​

2,143

​

​

2,343

Net operating loss and expenditure credit carryforwards

​

​

114,972

​

​

71,742

Other

​

​

260

​

​

237

Total

​

​

135,360

​

​

85,359

Valuation allowance

​

​

(132,443)

​

​

(82,398)

​

​

​

2,917

​

​

2,961

Net deferred tax asset/(liability)

​

$

—

​

$

—

​

Schedule of movements in deferred tax asset valuation allowance

The movements in the deferred tax asset valuation allowance for the year ended December 31, 2021 and 2020 are as follows (thousands):

​

​

​

​

​

​

​

​

​

2021

​

2020

Valuation allowance at January 1,

​

$

82,398

​

$

59,172

Increase in valuation allowance through net loss

​

​

50,046

​

​

23,025

Increase/(decrease) in valuation allowance through other comprehensive loss

​

​

1,512

​

​

(2,696)

Foreign exchange translation adjustments

​

​

(1,513)

​

​

2,897

​

​

$

132,443

​

$

82,398

Schedule of the effective tax rate reconciliation

Reconciliation of the U.K. statutory income tax rate to the Company's effective tax rate is as follows (in percentages):

​

​

​

​

​

​

​

​

​

​

Year ended

​

Year ended

​

Year ended

​

​

​

December 31, 

​

December 31, 

​

December 31, 

​

​

    

2021

    

2020

    

2019

    

U.K. tax rate

​

19.0

%  

19.0

%  

19.0

%  

Tax-exempt reimbursable tax credits included within pretax Research and development expense

​

4.1

%  

2.8

%  

2.8

%  

Surrender of R&D expenditures for R&D tax credit refund

​

(10.3)

%  

(8.4)

%  

(7.7)

%  

Expenses not deductible

​

(0.2)

%  

(1.4)

%  

—

%  

Permanent differences for unrealized foreign exchange on intercompany loans of a long-term investment nature

​

—

%  

—

%  

(1.5)

%  

Change in valuation allowances

​

(31.8)

%  

(17.8)

%  

(12.4)

%  

Change in tax rates

​

18.1

%  

4.1

%  

—

%  

Difference in tax rates

​

—

%  

—

%  

(1.2)

%  

R&D tax credits generated

​

2.0

%

1.8

%  

1.5

%  

Other

​

(1.4)

%  

(0.1)

%  

(0.7)

%  

Effective income tax rate

​

(0.5)

%  

(0.0)

%  

(0.2)

%