| Summary of Significant Accounting Policies - Leases (Details) | 1 Months Ended | ||
|---|---|---|---|
| Jul. 31, 2015 | Aug. 31, 2021 | Sep. 30, 2015 | |
| Lease term (in years) | 15 years | ||
| Lease for Research and development facility in Oxfordshire, U.K. | |||
| Lease term (in years) | 25 years | ||
| Lease for Offices and Research facilities in Philadelphia, U.S. | |||
| Early termination option (in months) | 123 months | ||
| Lease of Building at Milton Park, Oxfordshire, United Kingdom | |||
| Lease term (in years) | 2 years | 
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- Definition Term of lessee's operating lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef 
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