| Revenue - Galapagos Collaboration (Details) - Galapagos Collaboration and Exclusive License Agreement - USD ($) | May 30, 2024 | Dec. 31, 2024 | 
|---|---|---|
| Revenue | ||
| Amount of transaction price of the agreement at inception | $ 100,000,000 | |
| Upfront payment received | 70,000,000 | |
| Aggregate amount of the transaction price that is allocated to performance obligations | $ 99,487,000 | |
| Proof of Concept Trial | ||
| Revenue | ||
| Aggregate amount of the transaction price that is allocated to performance obligations | 43,887,000 | |
| Material Right for the Exclusive Option | ||
| Revenue | ||
| Aggregate amount of the transaction price that is allocated to performance obligations | $ 55,600,000 | |
| Maximum | ||
| Revenue | ||
| Amount of option exercise fees | 100,000,000 | |
| Research and development | ||
| Revenue | ||
| Upfront payment received | 15,000,000 | |
| Milestone payments | 30,000,000 | |
| Potential milestone payments to be received | 15,000,000 | |
| Development and sales milestone | Maximum | ||
| Revenue | ||
| Potential amount of additional milestone payment | $ 465,000,000 | 
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- Definition Amount of future milestone payments that could be paid upon achievement of certain milestones per agreement. No definition available. 
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- Definition Represents the amount of milestone payments made by the entity under the license agreement. No definition available. 
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- Definition Fees due to the entity upon exercise of the option to obtain a license No definition available. 
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- Definition Represents the potential payment that may be received upon achievement of specified milestones per agreement. No definition available. 
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- Definition Amount of the transaction price of the agreement at inception. No definition available. 
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- Definition Amount of up-front payment received under terms of the agreement. No definition available. 
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. Reference 1: http://www.xbrl.org/2003/role/disclosureRef 
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- Definition Amount of transaction price allocated to performance obligation that has not been recognized as revenue. Reference 1: http://www.xbrl.org/2003/role/disclosureRef 
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