Quarterly report pursuant to Section 13 or 15(d)

UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

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UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Cash flows from operating activities    
Net loss $ (50,265) $ (37,763)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 1,386 1,436
Amortization 209  
Share-based compensation expense 5,586 5,334
Unrealized foreign exchange (gains)/losses (244) 1,249
Amortization on available-for-sale debt securities 999 1,499
Other 220 1,299
Changes in operating assets and liabilities:    
Increase in receivables and other operating assets (10,759) (11,155)
Increase/ (decrease) in payables and other current liabilities 964 (8,601)
(Decrease)/ increase in deferred revenue (2,497) 162
Net cash used in operating activities (54,401) (46,540)
Cash flows from investing activities    
Acquisition of property, plant and equipment (7,114) (1,152)
Acquisition of intangibles assets   (133)
Maturity or redemption of marketable securities 44,536 84,646
Investment in marketable securities (42,197) (61,599)
Net cash (used in)/ provided by investing activities (4,775) 21,762
Cash flows from financing activities    
Proceeds from exercise of stock options 35 534
Net cash provided by financing activities 35 534
Effect of currency exchange rate changes on cash, cash equivalents and restricted cash (1,270) (204)
Net decrease in cash, cash equivalents and restricted cash (60,411) (24,448)
Cash, cash equivalents and restricted cash at start of period 151,666 61,484
Cash, cash equivalents and restricted cash at end of period $ 91,255 $ 37,036