Quarterly report [Sections 13 or 15(d)]

Segment reporting

v3.25.2
Segment reporting
6 Months Ended
Jun. 30, 2025
Segment reporting  
Segment reporting

Note 14 – Segment reporting

The Company has one reportable segment relating to the research, development and commercialization of its novel cell therapies. The segment derives its current revenues from research and development collaborations.

The Company’s Chief Operating Decision Maker (the “CODM”), its Chief Executive Officer and the senior leadership team (comprising the Executive Team members and two senior vice presidents), manages the Company’s operations on an integrated basis for the purposes of allocating resources. When evaluating the Company’s financial performance, the CODM regularly reviews total revenues, total expenses and expenses by function and the CODM makes decisions using this information on a global basis.

The table below is a summary of the segment profit or loss, including significant segment expenses (in thousands):

Three months ended

Six months ended

June 30, 

June 30, 

2025

    

2024

2025

    

2024

Revenue

$

13,677

$

128,231

$

20,962

$

133,909

Less:

Cost of goods sold

(2,501)

(3,380)

0

Research

488

(3,830)

(1,620)

(7,438)

CMC and Quality

(10,510)

(14,159)

(22,595)

(28,933)

Biomarkers

(1,505)

(2,495)

(2,727)

(5,286)

Development and Compliance

(9,552)

(12,611)

(20,102)

(27,486)

Infrastructure management and Facilities

(6,977)

(7,749)

(14,316)

(15,828)

Commercial and Commercial planning

(3,946)

(2,561)

(8,344)

(6,445)

Support and corporate functions

(10,172)

(9,139)

(22,811)

(21,073)

Other segment income/(expenses), net(a)

710

(6,987)

(1,088)

(1,981)

Total operating expenses

(43,965)

(59,531)

(96,983)

(114,470)

Operating (loss)/profit

(30,288)

68,700

(76,021)

19,439

Interest income

233

1,376

1,143

2,721

Interest expense

(962)

(526)

(2,843)

(526)

Other income (expense), net

1,289

497

984

436

Income tax expense

(612)

(526)

(1,187)

(1,052)

Segment and consolidated net (loss)/profit

$

(30,340)

$

69,521

$

(77,924)

$

21,018

(a)Other segment income/(expenses) for the six months ended June 30, 2025 includes reimbursements receivable for research and development tax and expenditure credits of $3,901,000 (2024: $5,879,000), depreciation of $4,620,000 (2024: $5,457,000), amortization of $355,000 (2024: $115,000) and share-based compensation expenses (see Note 11).

The main measure of assets reviewed by the CODM is the Company’s cash and cash equivalents and marketable securities. Total cash outflows relating to additions to long-lived assets have been disclosed in the Consolidated Statements of Cash Flows as cash outflows from investing activities.