Annual report pursuant to Section 13 and 15(d)

Accrued expenses and other current liabilities (Details)

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Accrued expenses and other current liabilities (Details) - USD ($)
$ in Thousands
Dec. 31, 2018
Dec. 31, 2017
Accrued expenses and other current liabilities    
Accrued clinical and development expenditure $ 9,637 $ 10,065
Accrued employee expenses 7,553 6,592
Accrued rent and property expenses 426 1,856
VAT   5,741
Other accrued expenditure 2,422 2,590
Other liabilities 316 357
Total $ 20,354 $ 27,201