Quarterly report pursuant to Section 13 or 15(d)

CONDENSED CONSOLIDATED BALANCE SHEETS

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CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($)
$ in Thousands
Jun. 30, 2018
Dec. 31, 2017
Current assets    
Cash and cash equivalents $ 42,312 $ 84,043
Marketable securities - available-for-sale debt securities 86,716 124,218
Accounts receivable, net of allowance for doubtful accounts of $0 and $0   206
Other current assets and prepaid expenses (including current portion of clinical materials) 32,626 21,716
Total current assets 161,654 230,183
Restricted cash 4,195 4,253
Clinical materials 4,782 4,695
Property, plant and equipment, net 39,472 40,679
Intangibles, net 1,196 1,337
Total assets 211,299 281,147
Current liabilities    
Accounts payable 4,131 8,378
Accrued expenses and other accrued liabilities 21,457 27,201
Deferred revenue 16,722 38,735
Total current liabilities 42,310 74,314
Other liabilities, non-current 3,887 3,849
Total liabilities 46,197 78,163
Stockholders' equity    
Common stock - Ordinary shares par value ?0.001, 701,103,126 authorized and 566,496,400 issued and outstanding (2017: 701,103,126 authorized and 562,119,334 issued and outstanding) 860 854
Additional paid in capital 466,229 455,401
Accumulated other comprehensive loss (14,419) (21,641)
Accumulated deficit (287,568) (231,630)
Total stockholders' equity 165,102 202,984
Total liabilities and stockholders' equity $ 211,299 $ 281,147