v3.22.2.2
UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
9 Months Ended 12 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Dec. 31, 2021
Cash flows from operating activities      
Net loss $ (136,206) $ (119,232)  
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation 4,009 4,333  
Amortization 629    
Share-based compensation expense 14,294 15,802  
Unrealized foreign exchange gains (2,501) (213)  
Amortization on available-for-sale debt securities 2,165 4,094  
Other 765 2,239  
Changes in operating assets and liabilities:      
Increase in receivables and other operating assets (29,778) (31,809)  
Increase/(decrease) in payables and other current liabilities 15,200 (109)  
(Decrease)/increase in deferred revenue (12,388) 1,696 $ 46,567
Net cash used in operating activities (143,811) (123,199)  
Cash flows from investing activities      
Acquisition of property, plant and equipment (26,081) (4,558)  
Acquisition of intangibles assets (231) (181)  
Maturity or redemption of marketable securities 136,694 190,393  
Investment in marketable securities (42,197) (81,363)  
Net cash provided by investing activities 68,185 104,291  
Cash flows from financing activities      
Proceeds from issuance of common stock from offerings, net of commissions and issuance costs 11,422 2,529  
Proceeds from exercise of stock options 42 707  
Net cash provided by financing activities 11,464 3,236  
Effect of currency exchange rate changes on cash, cash equivalents and restricted cash (6,791) (1,177)  
Net decrease in cash, cash equivalents and restricted cash (70,953) (16,849)  
Cash, cash equivalents and restricted cash at start of period 151,666 61,484 61,484
Cash, cash equivalents and restricted cash at end of period $ 80,713 $ 44,635 $ 151,666

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