Company Information

Company Profile

Company Profile

Adaptimmune focused on designing and delivering novel cancer immunotherapy products. We utilize the body’s own machinery – the T-cell – to target and destroy cancer. We believe our therapies have the potential to significantly impact cancer treatment and the clinical outcomes for people with cancer.

We have developed a proprietary T-cell receptor (TCR) platform that enables us to identify cancer targets, as well as genetically engineer TCRs to recognize and attack these cancer targets. We engineer a patient’s own T-cells to express these affinity-enhanced TCRs, to produce TCR T-cell treatments.

We have a preclinical pipeline with multiple cell therapy approaches, including additional TCR targets, broader HLA coverage, HLA Independent TCR (HiTs) cell therapies that eliminate the need for HLA; and next-generation Tumor Infiltrating Lymphocyte (TIL) therapies.

Industry Classifications

Sector

Healthcare

Industry

Biotechnology

SIC

Pharmaceutical Preparations (2834)

Adaptimmune at a Glance

6

Responses in six solid tumor indications demonstrate SPEAR T-cell potential to treat cancer.

2022

The Company aims to submit a BLA for afami-cel for synovial sarcoma in 2022.

100s

Number of autologous product batches manufactured in-house at our Navy Yard facility (Philadelphia, PA) across multiple products and tumor types.

As of March 16 2022

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