Afami-cel

Overview

Afamitresgene autoleucel (afami-cel; formerly ADP-A2M4) is directed to a member of the MAGE family of cancer testis antigens expressed in a number of solid tumor cell types. The MAGE- A4 antigen is among the most commonly expressed cancer testis antigens.

Cancer indications in the SPEARHEAD-1 trial

Synovial Sarcoma

Soft tissue sarcomas can develop from soft tissues like fat, muscle, nerves, fibrous tissues, blood vessels, or deep skin tissues.

Myxoid/Round Cell Liposarcoma (MRCLS)

Soft tissue sarcomas can develop from soft tissues like fat, muscle, nerves, fibrous tissues, blood vessels, or deep skin tissues.

Publications

Review our findings and publications.

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Latest News

On November 11, 2021, we presented positive results from SPEARHEAD-1 trial in patients with synovial sarcoma and MRCLS at CTOS.

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