Afami-cel

Overview

Overview

Afamitresgene autoleucel (“afami-cel”; formerly ADP-A2M4) is directed to a member of the MAGE family of cancer testis antigens expressed in a number of solid tumor cell types. The MAGE- A4 antigen is among the most commonly expressed cancer testis antigens.

Cancer indications in the SPEARHEAD-1 trial

Synovial Sarcoma

Synovial Sarcoma

Soft tissue sarcomas can develop from soft tissues like fat, muscle, nerves, fibrous tissues, blood vessels, or deep skin tissues.

Myxoid/Round Cell Liposarcoma (MRCLS)

Myxoid/Round Cell Liposarcoma (MRCLS)

Soft tissue sarcomas can develop from soft tissues like fat, muscle, nerves, fibrous tissues, blood vessels, or deep skin tissues.

Publications

Review our findings and publications.