Adaptimmune Therapeutics plc is incorporated in England, pursuant to the laws of England and Wales. The company's registered number is 09338148.

Our headquarters are at 60 Jubilee Avenue, Milton Park, Abingdon, Oxfordshire OX14 4RX, UK.

Our financial year ends on December 31.

Our independent Registered Public Accounting firm is KPMG LLP.

Adaptimmune is not listed on a national securities exchange. Adaptimmune’s shares are quoted on the OTC Pink Limited Market under the ticker symbol “ADAPY” - https://www.otcmarkets.com/stock/ADAPY

Our IPO on Nasdaq occurred in May 2015. On October 28, 2025, Adaptimmune voluntarily delisted from Nasdaq and transferred to the OTC Pink Limited Market.

An American Depositary Receipt (ADR) is a negotiable instrument that represents ownership in securities of a non-US company; it is a mechanism designed to facilitate US trading of non-US securities.

ADRs are quoted and traded in US dollars in the US securities market. Also, the dividends, if any, are paid to investors in US dollars.

An American Depositary Share (ADS) is a US dollar-denominated share, evidenced by an ADR, which represents a specified number of underlying shares held in custody in the UK.

Adaptimmune's ADSs, each representing 6 Ordinary Shares, are quoted on the OTC Pink Limited Market under the ADAPY symbol.

An ADR is the actual receipt that is issued by a depositary bank representing ownership of a company's underlying ordinary shares. An ADR can represent any number of ADSs. The term "ADR" is often used to mean both the receipt and the securities themselves.

Adaptimmune's ADR programme is administered by Citibank N.A. and ADR enquiries may be directed to the address below:

Citibank Shareholder Services
P.O. Box 43099
Providence
Rhode Island
02940-5000
USA

Phone: +1-877-248-4237 (toll free within the USA)
International: +1-781-575-4555
Email: Citibank@shareholders-online.com
Or visit Citi's Depositary Receipts Services at: www.citi.com/dr

You can buy an ADR through a broker, just as you would any other U.S. securities. Adaptimmune does not currently have a direct ADR purchase plan.

The Adaptimmune ADR share price can be found on the OTC Pink Limited Market site at the following link: https://www.otcmarkets.com/stock/ADAPY

As an ADR holder on the record date, you will have the sole right to vote the equivalent number of underlying shares as represented by your Adaptimmune ADR holdings. You will receive your proxy card and other relevant documentation through your usual intermediary.

A registered holder is one whose name appears on the books of the depositary. The registered holder is considered the owner of record. A beneficial holder is one whose holdings are registered in a name other than their own, such as the name of a broker, bank or nominee account.

Please contact Citibank Shareholder Services when you move so that your account records can be updated. Phone: +1-877-248-4237 (toll free within the USA), International: +1-781-575-4555 during Monday-Friday 08:30 AM through 6:00 PM EST. Email: Citibank@shareholders-online.com

Adaptimmune has appointed Computershare Investor Services PLC as its Registrar. The Registrar manages Adaptimmune’s ordinary share register on its behalf. They are responsible for ensuring the shareholder details are recorded accurately.

For shareholder enquiries relating to your ordinary shareholding, such as changing your name, address, and ordinary share certificates, please contact our Registrar by writing to:

Computershare Investor Services PLC
The Pavilions
Bridgwater Road
Bristol
BS99 6ZZ
England
Tel: +44 (0) 370 702 0000
www.investorcentre.co.uk

Please visit the Investors & Media section of our website

Adaptimmune’s SEC filings can be viewed at the SEC Filings section of our website or at the SEC’s website

For investor-related questions, please send an email to IR@adaptimmune.com